Scott Edelman has published more than 85 short stories in magazines such as Postscripts, The Twilight Zone, Absolute Magnitude, The Journal of Pulse-Pounding Narratives, Science Fiction Review and Fantasy Book, and in anthologies such as Why New Yorkers Smoke, The Solaris Book of New Science Fiction: Volume Three, Crossroads: Southern Tales of theFantastic, Men Writing SF as Women, MetaHorror, Once Upon a Galaxy, Moon Shots, Mars Probes, Forbidden Planets, Summer Chills, and The Mammoth Book of Monsters. His most recent short story was published in the anthology The Monkey's Other Paw: Revived Classic Stories of Dread and the Dead.

A collection of his horror fiction, These Words Are Haunted, came out from Wildside Books in 2001, and a standalone novella, The Hunger of Empty Vessels, was published in 2009 by Bad Moon Books. He is also the author of the Lambda Award-nominated novel The Gift (Space & Time, 1990) and the collection Suicide Art (Necronomicon, 1992). His collection of zombie fiction, What Will Come After, came in 2010 from PS Publishing, and was a finalist for both the Stoker Award and the Shirley Jackson Memorial Award. His science fiction short fiction has been collected in What We Still Talk About from Fantastic Books.

He has been a Stoker Award finalist five times, both in the category of Short Story and Long Fiction. Additionally, Edelman worked for the Syfy Channel for more than thirteen years as editor ofScience Fiction Weekly, SCI FI Wire, and Blastr. He was the founding editor of Science Fiction Age, which he edited during its entire eight-year run. He also editedSCI FI magazine, previously known as Sci-Fi Entertainment, for more a decade, as well as two other SF media magazines, Sci-Fi Universe and Sci-Fi Flix. He has been a four-time Hugo Award finalist for Best Editor.

He worked as an assistant editor for Marvel Comics in the '70s, writing everything from display copy for superhero Slurpee cups to the famous Bullpens Bulletins pages. While there, he edited the Marvel-produced fan magazine FOOM (Friend of Ol' Marvel). He also wrote trade paperbacks such as The Captain Midnight Action Book of Sports, Health and Nutrition and TheMighty Marvel Fun Book.

In 1976, he left staff to go freelance, and worked for both Marvel and DC. His scripts appeared in Captain Marvel, Master of Kung Fu, Omega the Unknown, Time Warp,House of Mystery, Weird War Tales, Welcome Back, Kotter and others.

He has at various times served on the juries for both the Science Fiction and Fantasy Writers of America Nebula Short Fiction Awards and the Theodore Sturgeon Memorial Award. He has been the Editor in Residence at the Clarion SF Workshop in 1999 and 2003, and the Guest Editor at the Odyssey Writers Workshop in 1999. He was the Toastmaster for the 2000 Nebula Awards ceremony. He was the winner of the 2004 Sam Moskowitz Award for outstanding contributions to the field of science fiction fandom.